The four star Ayre Gran Colón Hotel is to be found near the Paseo del Arte where many of Madrid's most important museums, such as the Prado and the Thyssen are found. It is very near the Retiro Park and is well connected to the IFEMA exhibition centre area, the airport and the main bus and train stations. It also has direct access to the main traffic routes, such as the M-30, M-40, M-45 and M-50. Next to the hotel is the Sainz de Baranda metro station. This allows quick access to all parts of the city, as well as to the city centre itself.

The hotel offers its guests a total of 359 rooms. All have an exterior view and have a bathroom with hair dryer, telephone, interactive satellite television with pay channels, safety deposit box, central heating and air conditioning, mini bar and internet connection. Most of the rooms have a terrace and are wi-fi equipped.

Guests at the Ayre Gran Colón will be able to start the day by enjoying a buffet-type breakfast. Later, for lunch, they can choose between three different restaurants. There is an a la carte restaurant with 'buffet a la carte' which combines the buffet service of the first course and dessert with four dishes at the table as an option for the second course. The hotel also has a cafeteria and an American bar, a gym with panoramic views, a hairdresser, sauna, an ultra violet sun lounge, and private garage. During the summer months guests can make use of the summer terrace with a private garden of 1,000 square metres. The hotel has 14 meeting rooms available with a capacity of from eight to 350 people, fitted with the modern audiovisual media, where clients may hold any type of event, whether meetings or banquets, celebrations and weddings.

Board basis available at this hotel is bed and breakfast or room only.